The Big Lottery Fund has added £40m to its Well-being programme.
The funding will go toward projects that have already been awarded grants from the programme, which has been running for five years and was previously worth £160m.
It supports initiatives in England to increase the amount of physical activity people do, improve their eating habits and tackle their mental health problems, targeting areas with the greatest health inequalities.
The extra funding will build on the work of the programme and prolong the impact of the projects, the BLF said, and existing grant-holders have been invited to submit applications.
Nat Sloane, chair of Big Lottery Fund England, said: "Our £40m comes at a crucial time becasue recent research shows that cost is a barrier for many people when it comes to looking after their health and wellbeing.
"This will build on a range of free initiatives we have funded in the past five years that target people in deprived communities and have been proven to work well. It will directly help hundreds of thousands to lead healthier lifestyles and become more active."