The investment firm, previously known as Merrill Lynch, has again come out as the market leader, beating Newton Investment Management, which came second, and UBS AG in third place.
The CAF ranking, published annually, is based on an analysis of the top 500 charities and 500 grantmaking trusts. BlackRock not only leads the table with the highest number of clients in this category, 65, but also has the most funds under management (£3.3bn) and the greatest market share - 9 per cent.
Andrew Hunter Johnston, head of charities at BlackRock, said: "Our experience and the breadth of our client portfolio allow us to work with organisations of all sizes to ensure they meet their objectives, and the Merrill Lynch and Black- Rock merger has enhanced our performance."
The top 10 showed little significant movement on last year: Schroders, Cazenove and Sarasin Chiswell maintained their positions at fourth, sixth and ninth respectively. The biggest change was HSBC Investment's drop from seventh to tenth. Ron Green, senior manager in product development and distribution at CAF's Charity Financial Services, said researchers had noted charities were showing more interest in socially responsible investment since last year.
"In the past, charities tended to fear that SRI was going to compromise performance, but now they have realised that is not the case," he said.