The Children's Clinic, a charity that provides complimentary treatments to babies and children, is to unveil a £2.4 million appeal to construct a purpose-built headquarters in Brighton.
The charity has received £1 million seed funding from Allied Dunbar, and is also planning to approach more companies about sponsorship opportunities.
Local people using environmentally friendly materials and practices will build the therapy centre.
"We're raising money to build a 'healthy' building that will reflect the ethos and essential qualities of our charity,
said Tracey Poulton, fundraising director at the Children's Clinic. "An integral part of this process will be forging close links with the surrounding community and we'll be looking to raise funds from local residents as well as trusts and foundations."
A 'Tip Twice' campaign will run in local restaurants.
At present the charity operates from a building in Brighton and has a number of out reach clinics in the Brighton and Hove area.
It treats up to 100 children a week with conditions such as asthma, and deals with emotional and behavioural problems that may stem from bereavement.