The National Autistic Society says autistic jobseekers are "written off" by the employment and benefits system.
Action for Children says instances of child neglect are increasing.
The Princess Royal Trust for Carers and Crossroads Care says three-quarters of Government funds to provide respite for carers have not reached those in need.
One of Wales's oldest charities, the Swansea Astronomical Society, says it can no longer afford its observatory site.
Recycling network Freecycle splits from its US counterpart and considers applying for charitable status.