More than 100 jobs could be lost from the British Red Cross as part of a restructure it is hoped will bring savings of about £10m over the next three years.
The charity, which had an income of £261.8m in 2014 and employs 4,100 staff, said the changes were due in part to an anticipated fall in fundraised income.
A spokeswoman for the charity said it expected a significant impact on its fundraising income in the next few years, given a potential fall in direct marketing income of between 10 to 20 per cent due to changes in fundraising regulation. It would therefore change the way it fundraised in future, she said.
The changes are part of a corporate strategy for 2015 to 2019 called Refusing to Ignore People in Crisis.
The document says the charity’s operations and property teams have decided to sell or not renew the leases of 173 of the charity’s 675 buildings over the next four years. This will be offset by the acquisition of 38 new properties.
The strategy document says services will be delivered in a "radically different" way and although income is "expected to grow", this will "not be at the rate previously achieved".
The charity’s spokeswoman it needed to move with the times to ensure it could continue to meet demands on its services both at home and abroad.
She said that a formal HR consultation with affected employees was continuing.
"We are in the process of changing the way we work so that we are as efficient and effective as possible," she said.
"This includes better systems and processes, and changes to our structures that free-up our front-line teams to focus on delivering excellent services to people in crisis and our life-saving work.
"We are acutely aware that a change programme of this size will have an effect on our staff and volunteers. Change is never easy and it will take time.
"However, we are committed to making the process as open and consultative as possible and have actively involved our people in the process.
"We will know more about the plans, timelines and impact on our people in the coming weeks and months."