Up to 140 jobs could be at risk at Versus Arthritis, after the charity completed a review of its priorities and resources.
Third Sector understands that staff were told in a meeting earlier this week that more than one-third of the charity’s workforce could be at risk.
The charity’s latest accounts, for the year ending March 2020, show it employed on average nearly 350 employees at a cost of more than £12.8m.
The charity confirmed that between 120 and 140 roles could be affected, but stressed that the changes outlined in the review are yet to be finalised, and provisional estimates on job roles could change.
Ellen Miller, acting chief executive of Versus Arthritis, said the charity's staff had critical to its achievements over the past three years, and that the organisation would be open and transparent throughout the process.
She said: “We’ve completed a thorough review of our priorities and resources so that we can focus our activities in areas where we are uniquely placed to make a real difference to the lives of people with arthritis.
“We shared the details of the review with our staff, as we have all aspects of its work.
Miller added: “The details of the organisational changes needed to meet the review are not finalised.”
Employees were told at the meeting that those interested in voluntary redundancy could come forward before a formal consultation begins in the new year, Third Sector understands.
Miller said: “We have made provisional estimates on the number of job roles that may be impacted, but these may change depending on the number of staff taking up voluntary redundancy.
“The details of the new structure will form the basis for a formal consultation with our staff in the new year.
“Our staff have been critical to the achievements that we have made as a charity over the last three years and we will be open and transparent in our approach, observing and exceeding employment practices. “
In February this year Versus Arthritis pledged to work to become a “truly inclusive and anti-racist” organisation after an independent investigation into 14 allegations of racism and bullying concluded that employees might not have the confidence to raise such issues.