The Alzheimer’s Society is expecting to have to make up to 300 redundancies because of an estimated £45m loss of income over the next financial year.
The charity said it was expecting to have to cut the jobs, which represent 20 per cent of its workforce, because of the effects of the coronavirus pandemic on the organisation.
It said in a statement that it was considering how it might deliver as much impact as possible while spending significantly less money.
It said a workforce change programme was underway to decide the timescale for the potential job losses.
The charity said it would be looking at ways to improve and increase its digital offering, while reducing as many of its backroom functions as is safe and postponing some future research commitments.
It will also be reviewing its property portfolio to see if it can manage with less office accommodation.
The charity said people living with dementia across the UK had been hardest hit by coronavirus, with more than one in four deaths among people with a dementia diagnosis.
Despite the difficulties presented by the pandemic the Alzheimer’s Society has still taken more than 15,000 calls to its Dementia Connect Support Line, and made more than 100,000 specialist support calls since lockdown began, including the launch of a new service called Companion Calls.
Kate Lee, chief executive of the Alzheimer’s Society, said: “Since lockdown started we have had some tremendous highs and crushing lows, both inside the organisation but also within the wider dementia community.
“We know that despite the incredible efforts of care home staff, the sector was largely ignored by government during the first part of the crisis with devastating consequences.
“Families have been separated from loved ones for months and there is evidence that those with dementia, living in both residential care and at home, have declined significantly faster than expected, with social isolation a major factor in many carers and people living with dementia’s lives.”
Lee added that she was “incredibly proud of how the organisation has responded and excited about our future".