Voluntary sector organisations in 12 areas of England that support people with multiple needs have been awarded a share of £112m from the Big Lottery Fund.
Each area will receive grants totalling up to £10m over eight years to create better coordinated services and help people with multiple problems, including homelessness, mental health problems, addiction and reoffending, and who are living chaotic lives.
The BLF said the funding was aimed at ending the "revolving door of care" that is faced by many people with complex, multiple problems when they are passed between charities and services that cannot deal with their wide range of needs.
Funding will be given to a lead organisation in each of the 12 areas, which are mostly charities or housing associations.
Lead organisations in the partnerships include the homelessness charity Shelter, which will receive £10m for work in Manchester, the drug and alcohol charity Addaction, which will receive £10m to lead the partnership in Blackpool, the community interest company Resolving Chaos, which has been given £7.9m for work in the London boroughs of Lambeth, Southwark and Lewisham, and Changing Lives, formerly the Cyrenians, which has received £5.5m for work in Newcastle and Gateshead.
The partnerships consist of between nine and 22 organisations and are made up of organisations including local authorities, probation trusts, clinical commissioning groups and training providers.
The BLF said there were an estimated 60,000 adults in England with multiple needs and the grants would enable different services to form partnerships.
Nat Sloane, chair of BLF England, said: "We’ve worked with a range of charities, which tell us that the system is flawed – people are passed from pillar to post and the result is them rebounding in and out of A&E departments and criminal courts rather than being helped in an effective way by integrated support services.
"This £112m investment will end the revolving door of care for these vulnerable people and, rather than being drains on society, will allow them to become assets that benefit their communities and society as a whole."
Resolving Chaos carried out an assessment of the 15 "most chaotic" people in the three London boroughs, who had a long history of homelessness, illness, addiction, imprisonment and using crisis services. It said in two years the cost of the services used by the 15 people totalled £1.8m.