Monkhouse, who died of prostate cancer in 2003, appears in a graveyard beside his own grave. He says: "As a comedian I died many deaths. Prostate cancer I don't recommend."
The film, which is supported by Monkhouse's widow, aims to raise awareness of a disease that kills one British man every hour. The campaign also directs viewers to a dedicated microsite where they can pledge money to support the foundation.
A spokesman said the company that made the film, which has been launched to coincide with men's health week, had done £700,000-worth of work for free.
The watch the film, click here.