The Charity Commission for Northern Ireland is set to remove organisations from its register of charities for the first time.
The regulator said on Friday that five charities had been issued with 30-day public notices informing them of its intention to remove them from the register.
All of the charities have failed to submit annual reports for two years or more, and upon investigation the regulator found they either had not carried out any activities recently or had uncontactable trustees.
The CCNI said it was first time it had taken such action.
The charities are: 100 Help the Homeless; Friends of Grove Park; Portadown Pentecostal Fellowship; Fermanagh Women’s Network; and Building Bards.
Myles McKeown, head of enquiries and compliance at the CCNI, said: "The register must be kept accurate and up to date so the public have trust in the information it holds. It would be misleading for a charity to remain on the register if it is no longer in existence.
"While the commission is taking action in these cases, it’s equally important that all charity trustees ensure their register entry is accurate and reflective of the current situation."