The charity contacted solicitors and alerted trading standards officers in Manchester last week after small business owners reported receiving cold calls from a publishing company.
One complainant reported that the caller asked him to place an advert on a wall planner, implying that the cost of £249 would be divided between several charities, including Centrepoint. He added that the caller then became aggressive and instructed him not to call "the main charity number".
Peter Duffin, a senior trading standards officer in Manchester, refused to confirm whether his office was investigating the complaints. However, he did confirm that it had recently investigated several similar scams in the area.
Centrepoint has also been contacted by trading standards officers in Northumberland, alerting it to similar reports in the north east of England.