A man from Enfield who has competed in every London Marathon since he took up running in 1986 will be among the 34,000 participants taking part in the race this year.
John Wallace, 58, will be running dressed as Superman to raise money for the North London Hospice, which provides care for individuals with life-limiting conditions.
Wallace has raised more than £53,000 for a range of charities since he started running.
A number of famous faces from the world of sports and entertainment will also be taking part in this year’s event, including the former England footballer Michael Owen and the Olympic rowers Katherine Grainger and James Cracknell.
This year’s race is expected to benefit more than 1,300 organisations.
Anthony Nolan, the blood cancer charity, has been chosen as the official charity partner for 2014 and is hoping to raise more than £1m with its team of runners.
A number of world record attempts will be taking place at this year’s event. The Huddersfield Marathon Band will attempt to complete the fastest marathon by a marching band by finishing the course in less than 7 hours, 22 minutes and 55 seconds. The band is hoping to raise £60,000 for the deafblind charity Sense.
Tony Phoenix-Morrison, 49, from Tyneside, is aiming to break the world record for completing the course carrying a household appliance by finishing the race in less than five hours carrying a fridge. Phoenix-Morrison is raising money for Cancer Research UK.
About 1,200 volunteers from St John Ambulance will be on hand to assist the runners.
Nick Bitel, chief executive of the Virgin Money London Marathon, said: "All indications are that the fundraising figures for the 2014 Virgin Money London Marathon will hit another record-breaking amount, and will be up on last year’s figure of £53m."