According to an announcement on the BBC website, the "night of entertainment" will celebrate the people who are working through the coronavirus pandemic and support those affected by the virus.
“Throughout this extraordinary time the kindness and community spirit of people across the country has been outstanding,” said Ruth Davison, chief executive of Comic Relief.
“The Big Night In is the perfect opportunity to praise the heroes who are caring for us, feeding us and lifting our spirits as we continue to help people most in need.”
According to the announcement, money raised by the show will be split equally between Comic Relief and Children in Need.
The funds raised will also support local charities and projects “so they can continue to provide vital emergency support”, and people of all ages and backgrounds who have been affected by Covid-19.
“There will be more demand than ever for support from local charities," the announcement said. "This includes making sure people are safe from harm, mentally healthy and with access to food, warmth and shelter, as well as helping people stay connected, active and positive through these extraordinary times."
Simon Antrobus, chief executive of BBC Children in Need, said: “These are challenging times for all of us, and the pandemic will have a significant impact on the most vulnerable people in our society.
"The Big Night In will offer the chance for everyone to (virtually) get together to celebrate the kindness and heroism of those making a real difference in their communities, and to support people across the UK who need our help now more than ever.”
The Big Night In will be broadcast on Thursday 23 April at 7pm on BBC One and iPlayer.