Donor information organisation New Philanthropy Capital has made four employees redundant.
The charity has let four staff go in its research department as part of a general restructure of the organisation designed to cut costs.
Sue Wixley, head of communications and marketing at NPC, said: "We've been going through a strategic review, so it's part of a restructuring process.
"The restructuring was happening anyway, but there is a broader context of something that is affecting all charities. Like lots of organisations at the moment, we are having to think quite carefully about our costs."
The charity has appointed a head of strategy to help the organisation more clearly define its purpose and is also drawing up a strategic plan.