The organisation, which is a household name in India, has campaigned for children's rights for more than 25 years. It has raised £1.25bn to fund children's health and education projects in India since it was launched, and describes itself as an "enabling organisation, as opposed to an implementing one".
It aims to tackle the root causes of poverty by funding and training community-based NGOs across India.
Nina Munshi, a marketing and fundraising consultant working for CRY's UK office, said: "We will be targeting high net-worth individuals, corporate partnerships and the open market. People connected to India feel a bond with our work there."
CRY is aiming to raise £100,000 in its first year, not just by targeting donors with advertisements in the Asian press and websites, but also with ads in mainstream press and news websites during festivals such as Diwali.
It also plans to hold a series of fundraising events.
The charity's UK move comes two years after the British launch of GiveIndia, an online scheme to promote and attract donors to Indian NGOs. The website allows users to browse a list of 100 NGOs working in a range of causes, find a volunteering opportunity or make a direct donation (Third Sector, 18 February 2004).
The Charity Commission is working on a research project looking at the numbers and categories of overseas charities and NGOs establishing UK offices. Spokeswoman Grace Money said the project was likely to find evidence of rapid growth in recent years.