The Dyslexia Institute is hoping to raise almost £28,000 from the sale of more than 150 modern bookplates, collected by the children's author Anne Fine.
Bookplates are illustrated labels upon which owners can write their name and attach to books in case of loss.
Children's Laureate from 2001-03, Fine has persuaded famous illustrators and cartoonists such as Raymond Briggs to help set up a website of freely downloadable modern bookplates.
Now, the originals of those bookplates have been donated to the Institute, which provides tuition and research for dyslexic people throughout the UK.
It raised £4,150 by auctioning five of the bookplates at the Dyslexia awards dinner in London last month. An original by Quentin Blake, the illustrator for Roald Dahl, sold for the highest price at £1,150.
The event, which celebrated 21 years of the charity's bursary fund, raised £120,000 from auctioning donated items. These included a private dinner with disgraced peer Jeffrey Archer, centre court tickets to Wimbledon and a JK Rowling-signed copy of the latest Harry Potter book.