A health and education centre in Iquitos, Peru, is among 24 overseas development projects to be funded by Lloyds TSB Foundation for Scotland.
Andrew Muirhead, chief executive of the foundation, said: "It is very difficult for Scottish charities working in overseas development to obtain funding because only 3 per cent of the UK's grant-making trusts' funding makes it north of the border."
The centre in Peru will be used by 30,000 people, and be built with £37,000 awarded to the Vine Trust, the largest grant to be handed out by the foundation.
The Trust began in 1999 when its founder, Reverend Willie McPherson, captained a ferry from Glasgow to Peru. It brought vital resources, including the boat itself, to shanty towns on the Amazon, which can only be reached by boat.
Smaller charities such as the Edinburgh-based Sunseed Tanzania Trust received £18,200 to help improve the quality of people's lives and environment.