David Praill, chief executive of the membership charity Hospice UK, will retire in July after 18 years in the role.
The charity, which supports organisations that provide or support hospice care in the UK and has more than 200 members, said that Praill had led Hospice UK through a period of significant growth.
It said that his achievements included developing the charity’s grants programme and launching its ehospice news and information service for hospice and palliative care.
The charity also changed its name from Help the Hospices under Praill’s oversight.
Lord Howard of Lympne, chair of Hospice UK, thanked Praill for his "immense contribution" to the charity’s work over the past 18 years.
"During that time he has spearheaded key organisational changes to our governance structures, established and developed our grant programmes to support hospice care and led several successful initiatives to move end-of-life care higher up the national agenda," he said. "We are deeply grateful for all that David has achieved and for his long-standing and tireless dedication to the hospice care sector."
Praill said it had been a privilege to lead the charity, but the time had come for a change.
"I have enjoyed an extraordinarily rewarding career in the hospice care sector and am proud of what has been achieved, both in supporting hospices and promoting hospice care more widely, in the UK and overseas.
"In recent years and following its recent rebrand and new campaigning focus, Hospice UK has created a stronger national voice for hospice care. There is much more to be done and I look forward to seeing it grow from strength to strength in the coming years."