The change is part of a new image intended to reflect the charity's increased provision of social as well as medical care, convey a clearer and more inclusive message about its activities and pave the way for a doubling of its annual income to £200m.
The rebrand coincides with the publication today of Worried Sick: The Emotional Impact of Cancer, a Macmillan survey revealing high levels of depression, anxiety and damage to relationships.
Peter Cardy, chief executive of Macmillan Cancer Support, said the review had concluded that most people still associated the charity with its nurses.
"But we've been proliferating into the social, everyday life aspects of cancer," he said. "If you look at the needs of people with cancer, it's not just the medical side that matters, but everything that follows - the social, psychological and financial aspects.
"Our direction has changed a lot since five years ago, when social care comprised only 10 per cent of our work. We've now set a goal of 25 per cent.
"The underlying issue is that we know we provide some sort of support to a third of a million people, but there are 1.25 million affected by cancer at any one time, and we want to reach them."
Cardy said the charity had spent £120,000 on design work intended to make clearer what services it provides and make it seem less academic and more accessible and inclusive. "We want to be a movement, not just an organisation," he said.
Meanwhile, cancer information charity Cancerbacup has rebranded as Cancerbackup and is launching the first nationally available audio tapes on cancer.
Cardy said the simultaneous rebranding was a coincidence. Asked why the two charities did not merge, he said it would "reduce the number of offers available. Each of the two charities has a different tone of voice and offers different kinds of information."