After a ruling by the Radio Advertising Clearance Centre, the ad, in which Gervais poses as a doctor conducting a digital rectal examination, has had its 'squish' sound effect removed and can only be played after the 9pm watershed in any case.
John Neate, PCC's chief executive, said: "We do not believe this ad is offensive. That the RACC wants to stand in the way of that is draconian, unnecessary and completely unacceptable."
The RACC said the advert could cause offence to some listeners because it was too graphic.
"The PCC could have done a daytime ad that had more innuendo, rather than an anal check-up," a spokesman said.
The ad kickstarts the charity's Real Men Know All About It campaign and coincides with a change in its logo to include the figure of a man forming the letter T in its title.
- Last week, we inadvertently called the Prostate Cancer Charity the Prostate Cancer Campaign. We apologise for the error.