The HIV and sexual health charity the Terrence Higgins Trust has appointed Rosemary Gillespie as its next chief executive.
Gillespie will join the trust in April leaving her post as chief executive of the HIV awareness charity Avert.
She takes over from Sir Nick Partridge, who left in October after almost 30 years at the charity, which had an income of £20.3m in 2011/12.
Paul Ward, the charity’s deputy chief executive and acting chief executive, will leave in March because his role is being combined with the chief executive’s position.
Gillespie, who has also been deputy chief executive at Breast Cancer Care and chief executive of the Roy Castle Lung Cancer Foundation, said she was looking forward to working with staff and volunteers during the next stage of the charity’s development.
Professor Chris Bones, chair of trustees at the trust, said Gillespie would bring a "remarkable combination of clinical practice, health management and charity leadership at a critical time for our development".
He said: "No organisation can stay still in the current economic climate, and Dr Gillespie's track record of successful change and innovation across a number of sectors will help us meet the challenges ahead in HIV and the wider area of sexual health."