The charity beat runners-up Cancer Research UK and the Prostate Cancer Research Foundation.
The judges were impressed by Save the Children's commitment to sending fundraisers to visit projects so that they can communicate the charity's work with passion, and by the training and salaries it offers.
The award was one of 16 presented in front of an audience of 750 fundraisers at last night's ceremony, hosted by BBC sports presenter Chris Hollins.
The Prostate Cancer Research Foundation took the innovation award for its ‘Give a few Bob' campaign, which used posthumous messages from entertainer Bob Monkhouse about his battle with the disease.
The Art Fund won Best Use of Direct Mail for its campaign to raise £5m to buy Turner's watercolour the Blue Rigi for the nation.
Schoolboy Liam Fairhurst took Volunteer Fundraiser of the Year for raising more than £150,000 for Clic Sargent after recovering from cancer.
Michelle Wright, head of development at the London Symphony Orchestra, was named Best Up-And-Coming Fundraiser after doubling the charity's private sector income from £1.5m to more than £3m.
And the winners are...
- Lifetime Contribution Gill Raikes, National Trust
- Volunteer Fundraiser of the Year Liam Fairhurst
- Fundraising Team of the Year South Yorkshire Community Foundation
- Fundraising Charity to Work For Save the Children
- Up-And-Coming Fundraiser Michelle Wright, London Symphony Orchestra
- Fundraiser of the Year Michael Dent, WRVS
- Partnership Lloyds TSB Group/Breast Cancer Care
- Donor Development Campaign Help the Aged
- Local/ Regional Campaign South Yorkshire Flood Disaster Relief Fund
- Most Innovative Campaign Prostate Cancer Research Foundation
- Direct Mail The Art Fund
- Use of e-Media WSPA
- Face-to-Face Campaign VSO
- Legacy Fundraising National Trust
- Payroll Giving Woodland Trust
- Use of the Telephone Breakthrough Breast Cancer
Third Sector will publish pictures from the event tomorrow