The Spinal Injuries Association has shed eight full-time and nine part-time positions as part of a restructure prompted by what it called a "tough period".
Paul Smith, executive director of the association, said the charity had made eight full-time redundancies and created two posts, reducing its total head count from 42 to 36.
He said some of the redundancies resulted from areas of work reaching a natural conclusion while others derived from trusts being unwilling to continue funding.
The charity's national network of peer-support workers, who work an average of two days a week, had been halved from 18 to nine because of a fall in corporate donations.
The charity's overall income was at the same level as last year, Smith said.
"We have been through a tough period, but we are very hopeful for the future," he said.