The Christian youth charity has already scrapped its communications and PR team and is currently in the process of negotiating further redundancies in other departments. Negotiations are expected to conclude next week.
Among those who have already gone is Josephine Carlsson, who was appointed YMCA England's first director of communications and PR last April (Third Sector, 23 March 2006).
A source close to the charity said the redundancies were the result of "dire financial problems".
Angela Sarkis, national secretary for YMCA England, confirmed the job cuts but said negotiations were not yet concluded.
"We have been restructuring the organisation for the past six months," she said. "We are restructuring to make YMCA more efficient and effective."
Sarkis said a full redundancy headcount would not be available until after negotiations had closed, but she did not deny that 20 people were in line to go. She said the total was a "very small proportion" of YMCA's staff.