The palliative care charity said the members of the provisionally titled London Committee will use their connections and skills to organise ambitious awareness and fundraising events.
The founding members of the committee are Merryn Corcoran and Sarah Watters-Carver, who are joint owners of Shoe Queen, an internet company that sells footwear. They will host a launch event on 8 March called Cocktails and Shoes.
The third 'uber-volunteer' is Di Green, who has 20 years' experience in marketing and events. She has helped to organise events such as London Fashion Week, and the charity hopes her expertise will help it improve its own functions.
Sue Ryder Care is setting up another committee, too.
The new committee is for younger Londoners, and will be open to everyone from graduates to thirty-somethings.
Victoria Glover, events and sponsorship manager at Sue Ryder Care, who is co-ordinating the London Committee, explained: "We have always focused on regional fundraising but have never had a London presence.
"The committee members will be the volunteer equivalent of our high-level donors, and the idea is to get them to interact by helping to organise flagship events.
"We are trying to build a network from contacts instead of cold calls."
The first meeting of the committee for younger Londoners will also be held in March. The charity plans to recruit members through ads in specialist magazines.